The Indian Express | 1 week ago | 18-03-2023 | 01:45 pm
These days we are barraged with a bewildering array of alphanumerics: H3N2, H2N2, H1N1 and of course the unforgettable SARS-CoV-2. These combinations are complex enough to serve as highly secure passwords to enter our bodies’ operating systems, lull us into complacency, terrorise us with déjà vu or possibly even all of the above. Should we be worried?Influenza viruses have co-existed with humanity at least since 6,000 BC in China, with Greek writings of fifth century BC indicating illness descriptions that match influenza. However, the influenza virus was first discovered only in 1931 by Richard Shope as a cause for swine influenza, a new disease among pigs at the time. By 1933, influenza A viruses were identified as being responsible for human infection, with multiple subtypes being discovered in subsequent years. Influenza B was discovered in 1940, and Influenza C and D were identified thereafter.The mother of all pandemics, The Spanish Influenza of 1918-1919, was caused by one such virus. It resulted in over 100 million deaths, the equivalent of 480 million deaths today. The 1957-58 Asian flu pandemic caused by the H2N2 virus resulted in over two million deaths, the equivalent of about 7.5 million deaths today. The 1968 Hong Kong Flu pandemic caused by the H3N2 virus resulted in over a million deaths. The 2009 Swine Flu pandemic caused by the H1N1 virus resulted in half a million deaths. We are all too familiar with the ongoing COVID-19 pandemic caused by the SARS-CoV-2 virus which has already resulted in approximately eight million deaths. All these viruses have mutated into less lethal avatars, which are gallivanting across the globe, resulting in several million infections and more than a million deaths every year. So, why shouldn’t we be worried?First, these are all weakened viruses with varying degrees of infectivity but very low rates of lethality. Next, the RT-PCR test has now become sophisticated enough to detect these viruses. Third, we have effective vaccines. Fourth, we’ve learnt a few things from experience.In late December 2022 and early January 2023, an outbreak of a respiratory infection with symptoms of a cold, sore throat, fever, and weariness was noticed within India. On March 4, the Indian Council of Medical Research (ICMR) announced that the disease had been caused by influenza virus subtype H3N2, a virus made of the N2 from the 1957 H2N2 virus and the H3 from the Avian Influenza A virus.COVID-19, as we know only too well, is brought on by the SARS-CoV-2 virus. The symptoms of all flu variants and those of COVID-19 are fairly similar. They include fever, stuffy nose, sore throat, fatigue, and headache. There are minor variations in predominance of symptoms and in recovery periods ranging from one to two weeks. Laboratory testing with the new RT-PCR tests is necessary for a precise diagnosis in order to pinpoint the genetic or molecular elements of the virus. Testing certainly helps on an epidemiological level to track and monitor disease prevalence but is of minimal significance in formulating an individual’s treatment plan.We are currently dealing with at least four, possibly more influenza viruses in addition to SARS-CoV-2. All of them are contagious and spread through droplets. Hence the prevention of all of them is similar. Precautions that reverberated as slogans during the COVID-19 pandemic plead to be re-established. Use of masks, hand and respiratory hygiene and social distancing are the best measures to curb the spread of all four viruses. I haven’t given up yet on masking and hand hygiene much to the amusement of many of my friends and some colleagues. Then again, call it luck, genes, vaccination, appropriate protocols, or combinations thereof but I have been spared COVID-19 and flu in all these years.What does one do if ill other than the obvious medical consultation? Bed rest, isolation, hydration, ventilation and symptomatic treatment for fever, sore throat, body ache, cough and other symptoms. Hospitalisation may be considered if not better in 7-10 days and deemed necessary by one’s physician. But unless there is secondary bacterial infection, absolutely no antibiotics. Certainly not the ones recommended by the friendly neighbourhood chemist! Antibiotics do not work on viruses. On the other hand, they do an incredibly sinister job of fostering antibiotic resistance which is growing to become a monumental problem in healthcare. Please avoid them unless deemed necessary by your physician. If indicated, antiviral drugs such as Tamiflu are known to facilitate recovery.One cannot help wondering if Lord Gautam Buddha might have anticipated the romp of multiple viruses when he advocated the golden middle path? Between recklessness and excessive caution, untampered bravado and paralytic anxiety, audacity and timidity lies our salvation.
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